Best Bets for NCAA Basketball Picks Against the Spread for Wednesday, December 4

Published 8:33 pm Tuesday, December 3, 2024

ATS Pick: Pittsburgh +5.5 vs. Mississippi State

• Matchup: Pittsburgh Panthers at Mississippi State Bulldogs
• Time: 9:15 PM ET
• Date: December 4
• Computer Projection: Pittsburgh by 1.3 points (Bet now on BetMGM)
• Spread: Mississippi State (-5.5)
• TV Channel: SEC Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: DePaul +14.5 vs. Texas Tech

• Matchup: DePaul Blue Demons at Texas Tech Red Raiders
• Time: 9:15 PM ET
• Date: December 4
• Computer Projection: Texas Tech by 7.9 points (Bet now on BetMGM)
• Spread: Texas Tech (-14.5)
• TV Channel: ESPNU
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: Memphis -10.5 vs. Louisiana Tech

• Matchup: Louisiana Tech Bulldogs at Memphis Tigers
• Time: 8:00 PM ET
• Date: December 4
• Computer Projection: Memphis by 16.5 points (Bet now on BetMGM)
• Spread: Memphis (-10.5)
• TV Channel: ESPN+
• Live Stream: Watch this game on ESPN+

ATS Pick: Kansas -2.5 vs. Creighton

• Matchup: Kansas Jayhawks at Creighton Bluejays
• Time: 8:30 PM ET
• Date: December 4
• Computer Projection: Kansas by 6.9 points (Bet now on BetMGM)
• Spread: Kansas (-2.5)
• TV Channel: Fox Sports 1
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: Marquette +6.5 vs. Iowa State

• Matchup: Marquette Golden Eagles at Iowa State Cyclones
• Time: 8:00 PM ET
• Date: December 4
• Computer Projection: Iowa State by 2.1 points (Bet now on BetMGM)
• Spread: Iowa State (-6.5)
• TV Channel: ESPN+
• Live Stream: Watch this game on ESPN+

Bet on this or any men’s college basketball matchup at BetMGM.

ATS Pick: Holy Cross +2.5 vs. Harvard

• Matchup: Harvard Crimson at Holy Cross Crusaders
• Time: 6:00 PM ET
• Date: December 4
• Computer Projection: Holy Cross by 1.8 points (Bet now on BetMGM)
• Spread: Harvard (-2.5)
• TV Channel: ESPN+
• Live Stream: Watch this game on ESPN+

ATS Pick: Gardner-Webb +4.5 vs. Wofford

• Matchup: Gardner-Webb Runnin’ Bulldogs at Wofford Terriers
• Time: 7:00 PM ET
• Date: December 4
• Computer Projection: Wofford by 0.5 points (Bet now on BetMGM)
• Spread: Wofford (-4.5)
• TV Channel: ESPN+
• Live Stream: Watch this game on ESPN+

ATS Pick: Seton Hall -16.5 vs. NJIT

• Matchup: NJIT Highlanders at Seton Hall Pirates
• Time: 8:30 PM ET
• Date: December 4
• Computer Projection: Seton Hall by 20.3 points (Bet now on BetMGM)
• Spread: Seton Hall (-16.5)
• TV Channel: CBS Sports Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: Utah State -17.5 vs. Wyoming

• Matchup: Wyoming Cowboys at Utah State Aggies
• Time: 9:00 PM ET
• Date: December 4
• Computer Projection: Utah State by 21.3 points (Bet now on BetMGM)
• Spread: Utah State (-17.5)
• TV Channel: MW Network

ATS Pick: Baylor +2.5 vs. UConn

• Matchup: Baylor Bears at UConn Huskies
• Time: 6:30 PM ET
• Date: December 4
• Computer Projection: Baylor by 1.2 points (Bet now on BetMGM)
• Spread: UConn (-2.5)
• TV Channel: Fox Sports 1
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)